Intracranial Rosai-Dorfman Disease in Pregnancy: A Case Report

نویسندگان

Ratul Raychaudhuri

Sarah Hackman

Thorkild Norregaard

چکیده

Rosai-Dorfman disease (RDD) is a well-described entity that rarely presents as a solitary intracranial mass. In this case report, we describe progesterone receptor (PR) positivity on immunostain in a recently pregnant patient. The possibility of meningioma was raised. However, the presence of emperipolesis and positive S100 staining in combination with negative EMA stain excluded meningioma from the differential. Additional cases of RDD underwent immunostain for PR and were found to be negative. We also present a review of the literature regarding dural based masses and discuss the limited literature regarding the treatment of solitary intracranial RDD.

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